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» Overestimation for Multiple Sequence Alignment
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CIBCB
2007
IEEE
13 years 11 months ago
Overestimation for Multiple Sequence Alignment
Abstract— Multiple sequence alignment is an important problem in computational biology. A-star is an algorithm that can be used to find exact alignments. We present a simple mod...
Tristan Cazenave
BMCBI
2010
138views more  BMCBI 2010»
13 years 5 months ago
Sigma-2: Multiple sequence alignment of non-coding DNA via an evolutionary model
Background: While most multiple sequence alignment programs expect that all or most of their input is known to be homologous, and penalise insertions and deletions, this is not a ...
Gayathri Jayaraman, Rahul Siddharthan
BMCBI
2006
156views more  BMCBI 2006»
13 years 5 months ago
Detecting the limits of regulatory element conservation and divergence estimation using pairwise and multiple alignments
Background: Molecular evolutionary studies of noncoding sequences rely on multiple alignments. Yet how multiple alignment accuracy varies across sequence types, tree topologies, d...
Daniel A. Pollard, Alan M. Moses, Venky N. Iyer, M...
BMCBI
2007
135views more  BMCBI 2007»
13 years 5 months ago
Automatic extraction of reliable regions from multiple sequence alignments
Background: High quality multiple alignments are crucial in the transfer of annotation from one genome to another. Multiple alignment methods strive to achieve ever increasing lev...
Timo Lassmann, Erik L. L. Sonnhammer
BIOCOMP
2006
13 years 6 months ago
PAC: Progressive Alignment with Consensus Sequences
Computation of multiple sequence alignments is one of the major open problems in computational molecular biology. The purpose of this study was to provide a new method, PAC (Progre...
Ke Liu, Mansur H. Samadzadeh