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» Pathway Analyst--Automated Metabolic Pathway Prediction
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CIBCB
2005
IEEE
13 years 6 months ago
Pathway Analyst--Automated Metabolic Pathway Prediction
—Metabolic pathways are crucial to our understanding of biology. The speed at which new organisms are being sequenced is outstripping our ability to experimentally determine thei...
Luca Pireddu, Brett Poulin, Duane Szafron, Paul Lu...
BIBE
2007
IEEE
145views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Homomorphisms of Multisource Trees into Networks with Applications to Metabolic Pathways
Network mapping is a convenient tool for comparing and exploring biological networks; it can be used for predicting unknown pathways, fast and meaningful searching of databases, a...
Qiong Cheng, Robert W. Harrison, Alexander Zelikov...
BMCBI
2010
115views more  BMCBI 2010»
13 years 5 months ago
Machine learning methods for metabolic pathway prediction
Background: A key challenge in systems biology is the reconstruction of an organism's metabolic network from its genome sequence. One strategy for addressing this problem is ...
Joseph M. Dale, Liviu Popescu, Peter D. Karp
GECCO
2005
Springer
124views Optimization» more  GECCO 2005»
13 years 10 months ago
Evolving petri nets to represent metabolic pathways
Given concentrations of metabolites over a sequence of time steps, the metabolic pathway prediction problem seeks a set of reactions and rate constants for them that could yield t...
Jeremiah Nummela, Bryant A. Julstrom
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
13 years 11 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka