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» Pathway Logic: Executable Models of Biological Networks
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ILP
2005
Springer
13 years 11 months ago
Machine Learning for Systems Biology
In this paper we survey work being conducted at Imperial College on the use of machine learning to build Systems Biology models of the effects of toxins on biochemical pathways. Se...
Stephen Muggleton
CMSB
2004
Springer
13 years 10 months ago
Modelling Metabolic Pathways Using Stochastic Logic Programs-Based Ensemble Methods
In this paper we present a methodology to estimate rates of enzymatic reactions in metabolic pathways. Our methodology is based on applying stochastic logic learning in ensemble le...
Huma Lodhi, Stephen Muggleton
BIOCOMP
2006
13 years 6 months ago
Petri Net Based Model Of The T Cell Receptor Signaling Pathway
Intracellular signaling pathways as well as the interactions and coordination that exist among them are complex and difficult to visualize and understand. Computer-based models of...
Srinidhi Jayasuryan, Anil Bamezai, Vijay Gehlot
RECOMB
2009
Springer
14 years 6 months ago
Evaluating Between-Pathway Models with Expression Data
Abstract. Between-Pathway Models (BPMs) are network motifs consisting of pairs of putative redundant pathways. In this paper, we show how adding another source of high-throughput d...
Benjamin J. Hescott, Mark D. M. Leiserson, Lenore ...
CISIS
2009
IEEE
14 years 6 days ago
A Nonmonotonic Logical Approach for Modelling and Revising Metabolic Networks
—This paper describes a new logic-based approach for representing and reasoning about metabolic networks. First it shows how biological pathways can be elegantly represented in a...
Oliver Ray, Ken E. Whelan, Ross D. King