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» PoPS: A Computational Tool for Modeling and Predicting Prote...
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CSB
2004
IEEE
115views Bioinformatics» more  CSB 2004»
13 years 8 months ago
PoPS: A Computational Tool for Modeling and Predicting Protease Specificity
Proteases play a fundamental role in the control of intra- and extracellular processes by binding and cleaving specific amino acid sequences. Identifying these targets is extremel...
Sarah E. Boyd, Maria J. García de la Banda,...
CIBCB
2005
IEEE
13 years 6 months ago
Neuro-fuzzy Prediction of Biological Activity and Rule Extraction for HIV-1 Protease Inhibitors
— A fuzzy neural network (FNN) and multiple linear regression (MLR) were used to predict biological activities of 26 newly designed HIV-1 protease potential inhibitory compounds....
Razvan Andonie, Levente Fabry-Asztalos, Catharine ...
BMCBI
2007
155views more  BMCBI 2007»
13 years 4 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
BMCBI
2010
152views more  BMCBI 2010»
13 years 4 months ago
FITBAR: a web tool for the robust prediction of prokaryotic regulons
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
Jacques Oberto
SCFBM
2008
138views more  SCFBM 2008»
13 years 4 months ago
Epigrass: a tool to study disease spread in complex networks
Background: The construction of complex spatial simulation models such as those used in network epidemiology, is a daunting task due to the large amount of data involved in their ...
Flávio C. Coelho, Oswaldo G. Cruz, Cl&aacut...