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BIBM
2008
IEEE
112views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Predicting Protective Linear B-Cell Epitopes Using Evolutionary Information
Mapping B-cell epitopes plays an important role in vaccine design, immunodiagnostic tests, and antibody production. Because the experimental determination of B-cell epitopes is ti...
Yasser El-Manzalawy, Drena Dobbs, Vasant Honavar
BMCBI
2007
121views more  BMCBI 2007»
13 years 4 months ago
Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines
Background: In an epitope-based vaccine setting, the use of conserved epitopes would be expected to provide broader protection across multiple strains, or even species, than epito...
Huynh-Hoa Bui, John Sidney, Wei Li, Nicholas Fusse...
BMCBI
2011
12 years 8 months ago
Determinants of Antigenicity and Specificity in immune response for Protein Sequences
Background: Target specific antibodies are pivotal for the design of vaccines, immunodiagnostic tests, studies on proteomics for cancer biomarker discovery, identification of prot...
Yulong Wang, Wenjun Wu, Nicolas N. Negre, Kevin P....