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13 years 6 months ago
Search for a New Description of Protein Topology and Local Structure
A novel description of protein structure in terms of the generalized secondary structure elements (GSSE) is proposed. GSSE's are defined as fragments of the protein structure...
Lukasz Jaroszewski, Adam Godzik
BMCBI
2008
168views more  BMCBI 2008»
13 years 5 months ago
Predicting protein folding pathways at the mesoscopic level based on native interactions between secondary structure elements
Background: Since experimental determination of protein folding pathways remains difficult, computational techniques are often used to simulate protein folding. Most current techn...
Qingwu Yang, Sing-Hoi Sze
BMCBI
2006
101views more  BMCBI 2006»
13 years 5 months ago
Local protein structure prediction using discriminative models
Background: In recent years protein structure prediction methods using local structure information have shown promising improvements. The quality of new fold predictions has risen...
Oliver Sander, Ingolf Sommer, Thomas Lengauer
RECOMB
2008
Springer
14 years 5 months ago
Rapid and Accurate Protein Side Chain Prediction with Local Backbone Information
High-accuracy protein structure modeling demands accurate and very fast side chain prediction since such a procedure must be repeatedly called at each step of structure refinement....
Jing Zhang, Xin Gao, Jinbo Xu, Ming Li
BIRD
2008
Springer
159views Bioinformatics» more  BIRD 2008»
13 years 7 months ago
Exploration of Evolutionary Relations between Protein Structures
Abstract. We describe a new method for the exploration of evolutionary relations between protein structures. The approach is based on the ESSM algorithm for detecting structural mu...
Natalja Kurbatova, Juris Viksna