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AINA
2008
IEEE
13 years 11 months ago
Protein Structure Comparison and Alignment Using Residue Contexts
We introduce a method for comparing protein structures using the notion of residue contexts based on protein Cα-atom backbones. The residue context is derived from the set of vec...
Tobias Sayre, Rahul Singh
ISBRA
2010
Springer
13 years 2 months ago
Residue Contexts: Non-sequential Protein Structure Alignment Using Structural and Biochemical Features
The study of non-sequential alignments, with different connectivity of the aligned fragments in the proteins being compared can offer a more complete picture of the structural, evo...
Jay W. Kim, Rahul Singh
BMCBI
2004
141views more  BMCBI 2004»
13 years 4 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
BIOCOMP
2008
13 years 6 months ago
GIPSCo: A Method for Comparison of Protein Structures Based on Geometric Invariants
Protein structure comparison is important for elucidation of evolutionary relationships, function and functionally important amino acid residues. We propose Geometric Invariant bas...
Sandeep Deshmukh, Aniket Dalal, Pramod Wangikar
BMCBI
2005
123views more  BMCBI 2005»
13 years 4 months ago
PSI-BLAST-ISS: an intermediate sequence search tool for estimation of the position-specific alignment reliability
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...
Mindaugas Margelevicius, Ceslovas Venclovas