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CEC
2007
IEEE
13 years 9 months ago
Prediction of protein interactions by combining genetic algorithm with SVM method
This paper proposes a novel hybrid GA/SVM method that can predict the interactions between proteins intermediated by the protein-domain relations. Firstly, we represented a protein...
Bing Wang, Lu-Sheng Ge, Wen-You Jia, Li Liu, Fu-Ch...
NAR
2011
182views Computer Vision» more  NAR 2011»
12 years 8 months ago
PAIR: the predicted Arabidopsis interactome resource
The predicted Arabidopsis interactome resource (PAIR, http://www.cls.zju.edu.cn/pair/), comprised of 5990 experimentally reported molecular interactions in Arabidopsis thaliana to...
Mingzhi Lin, Xueling Shen, Xin Chen
ICML
2005
IEEE
14 years 6 months ago
Explanation-Augmented SVM: an approach to incorporating domain knowledge into SVM learning
We introduce a novel approach to incorporating domain knowledge into Support Vector Machines to improve their example efficiency. Domain knowledge is used in an Explanation Based ...
Qiang Sun, Gerald DeJong
BMCBI
2011
12 years 9 months ago
Determinants of Antigenicity and Specificity in immune response for Protein Sequences
Background: Target specific antibodies are pivotal for the design of vaccines, immunodiagnostic tests, studies on proteomics for cancer biomarker discovery, identification of prot...
Yulong Wang, Wenjun Wu, Nicolas N. Negre, Kevin P....
BICOB
2009
Springer
13 years 9 months ago
Constrained Fisher Scores Derived from Interaction Profile Hidden Markov Models Improve Protein to Protein Interaction Predictio
Protein-protein interaction plays critical roles in cellular functions. In this work, we propose a computational method to predict protein-protein interaction by using support vec...
Alvaro J. González, Li Liao