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» QTLminer: identifying genes regulating quantitative traits
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BMCBI
2010
96views more  BMCBI 2010»
13 years 5 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
RECOMB
2005
Springer
14 years 5 months ago
Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes
Background: Correlations between polymorphic markers and observed phenotypes provide the basis for mapping traits in quantitative genetics. When the phenotype is gene expression, ...
David Kulp, Manjunatha Jagalur
BIBE
2007
IEEE
121views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Identifying Genomic Regulators of Set-Wise Co-Expression
The genetical genomics approach has been used to study the genetic basis of variation in gene expression, where putative transcriptional regulators of genes are identified via gene...
Jung Hoon Woo, Tian Zheng, Ju Han Kim
RECOMB
2005
Springer
14 years 5 months ago
Combinatorial Genetic Regulatory Network Analysis Tools for High Throughput Transcriptomic Data
: A series of genome-scale algorithms and high-performance implementations is described and shown to be useful in the genetic analysis of gene transcription. With them it is possib...
Elissa J. Chesler, Michael A. Langston
BMCBI
2007
103views more  BMCBI 2007»
13 years 5 months ago
eQTL Viewer: visualizing how sequence variation affects genome-wide transcription
Background: Expression Quantitative Trait Locus (eQTL) mapping methods have been used to identify the genetic basis of gene expression variations. To map eQTL, thousands of expres...
Wei Zou, David L. Aylor, Zhao-Bang Zeng