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» QTLminer: identifying genes regulating quantitative traits
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BIBM
2008
IEEE
111views Bioinformatics» more  BIBM 2008»
14 years 8 days ago
Estimating Regulatory Associations of Genomic Loci and Biological Pathways in Lymphoblastoid Cells
Genetical genomics has been established to study genetic variation of gene expression. It treats transcript expression as a quantitative trait and identifies putative regulatory l...
Jung Hoon Woo, Eunjee Lee, Sung-Bum Cho, Ju Han Ki...
BMCBI
2006
86views more  BMCBI 2006»
13 years 5 months ago
Identification of QTLs controlling gene expression networks defined a priori
Background: Gene expression microarrays allow the quantification of transcript accumulation for many or all genes in a genome. This technology has been utilized for a range of inv...
Daniel J. Kliebenstein, Marilyn A. L. West, Hans v...
EVOW
2008
Springer
13 years 7 months ago
Detection of Quantitative Trait Associated Genes Using Cluster Analysis
Abstract. Many efforts have been involved in association study of quantitative phenotypes and expressed genes. The key issue is how to efficiently identify phenotype-associated gen...
Zhenyu Jia, Sha Tang, Dan Mercola, Shizhong Xu
BMCBI
2010
120views more  BMCBI 2010»
13 years 5 months ago
Modeling expression quantitative trait loci in data combining ethnic populations
Background: Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to...
Ching-Lin Hsiao, Ie-Bin Lian, Ai-Ru Hsieh, Cathy S...
BMCBI
2004
142views more  BMCBI 2004»
13 years 5 months ago
GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies
Background: Microarray and other high-throughput technologies are producing large sets of interesting genes that are difficult to analyze directly. Bioinformatics tools are needed...
Bing Zhang, Denise Schmoyer, Stefan Kirov, Jay Sno...