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» Query-driven module discovery in microarray data
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BIOINFORMATICS
2007
42views more  BIOINFORMATICS 2007»
13 years 4 months ago
Query-driven module discovery in microarray data
Thomas Dhollander, Qizheng Sheng, Karen Lemmens, B...
DILS
2008
Springer
13 years 6 months ago
Semi Supervised Spectral Clustering for Regulatory Module Discovery
We propose a novel semi-supervised clustering method for the task of gene regulatory module discovery. The technique uses data on dna binding as prior knowledge to guide the proces...
Alok Mishra, Duncan Gillies
BMCBI
2007
146views more  BMCBI 2007»
13 years 4 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
RECOMB
2006
Springer
14 years 4 months ago
Genome-Wide Discovery of Modulators of Transcriptional Interactions in Human B Lymphocytes
Abstract. Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription fa...
Kai Wang, Ilya Nemenman, Nilanjana Banerjee, Adam ...
BMCBI
2007
227views more  BMCBI 2007»
13 years 4 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...