Sciweavers

31 search results - page 2 / 7
» Rank-invariant resampling based estimation of false discover...
Sort
View
BMCBI
2011
13 years 2 days ago
Sequential Interim Analyses of Survival Data in DNA Microarray Experiments
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Andreas Leha, Tim Beißbarth, Klaus Jung
BMCBI
2005
121views more  BMCBI 2005»
13 years 5 months ago
Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...
Kerby Shedden, Wei Chen, Rork Kuick, Debashis Ghos...
APBC
2004
107views Bioinformatics» more  APBC 2004»
13 years 7 months ago
An Empirical Bayes Adjustment to Multiple p-values for the Detection of Differentially Expressed Genes in Microarray Experiments
In recent microarray experiments thousands of gene expressions are simultaneously tested in comparing samples (e.g., tissue types or experimental conditions). Application of a sta...
Somnath Datta, Susmita Datta
RECOMB
2006
Springer
14 years 5 months ago
Permutation Filtering: A Novel Concept for Significance Analysis of Large-Scale Genomic Data
Permutation of class labels is a common approach to build null distributions for significance analyis of microarray data. It is assumed to produce random score distributions, which...
Stefanie Scheid, Rainer Spang
BMCBI
2010
132views more  BMCBI 2010»
13 years 5 months ago
Parallel multiplicity and error discovery rate (EDR) in microarray experiments
Background: In microarray gene expression profiling experiments, differentially expressed genes (DEGs) are detected from among tens of thousands of genes on an array using statist...
Wayne Wenzhong Xu, Clay J. Carter