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» Rearrangement Models and Single-Cut Operations
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RECOMB
2009
Springer
13 years 11 months ago
Rearrangement Models and Single-Cut Operations
Abstract. There have been many widely used genome rearrangement models, such as reversals, HannenhalliPevzner, and double-cut and join. Though each one can be precisely defined, t...
Paul Medvedev, Jens Stoye
FUIN
2008
96views more  FUIN 2008»
13 years 4 months ago
Computational Efficiency of Intermolecular Gene Assembly
In this paper, we investigate the computational efficiency of gene rearrangement operations found in ciliates, a type of unicellular organisms. We show how the so-called guided re...
Tseren-Onolt Ishdorj, Remco Loos, Ion Petre
RECOMB
2008
Springer
14 years 5 months ago
On Computing the Breakpoint Reuse Rate in Rearrangement Scenarios
In the past years, many combinatorial arguments have been made to support the theory that mammalian genome rearrangement scenarios rely heavily on breakpoint reuse. Different model...
Anne Bergeron, Julia Mixtacki, Jens Stoye
DNA
2005
Springer
117views Bioinformatics» more  DNA 2005»
13 years 10 months ago
Simple Operations for Gene Assembly
Abstract. The intramolecular model for gene assembly in ciliates considers three operations, ld, hi, and dlad that can assemble any gene pattern through folding and recombination: ...
Tero Harju, Ion Petre, Vladimir Rogojin, Grzegorz ...
RECOMB
2008
Springer
14 years 5 months ago
Perfect DCJ Rearrangement
We study the problem of transforming a multichromosomal genome into another using Double-Cut-and-Join (DCJ) operations. We introduce the notion of DCJ scenario that does not break ...
Sèverine Bérard, Annie Chateau, Cedr...