Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorit...
Jian Ma, Aakrosh Ratan, Brian J. Raney, Bernard B....
It is often impossible to sequence all descendent genomes to reconstruct an ancestral genome. In addition, more genomes do not necessarily give a higher accuracy for the reconstruc...
Abstract. Whole genome doubling (WGD), a frequent occurrence during the evolution of the angiopsperms, complicates ancestral gene order reconstruction due to the multiplicity of so...
David Sankoff, Chunfang Zheng, P. Kerr Wall, Claud...