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» Responses of Fluctuating Biological Systems
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CCE
2005
13 years 5 months ago
Numerical simulation of stochastic gene circuits
Armed with increasingly fast supercomputers and greater knowledge of the molecular mechanisms of gene expression, it is now practical to numerically simulate complex networks of r...
Howard Salis, Yiannis N. Kaznessis
CCE
2008
13 years 6 months ago
Identification of regulatory mechanisms of the hepatic response to thermal injury
The purpose of this paper is to evaluate the hypothesis that a systems biology approach can be developed such that a set of transcription factors, relevant to burn-induced inflamm...
Eric Yang, Timothy Maguire, Martin L. Yarmush, Fra...
DIS
2010
Springer
13 years 4 months ago
An Artificial Experimenter for Enzymatic Response Characterisation
Identifying the characteristics of biological systems through physical experimentation, is restricted by the resources available, which are limited in comparison to the size of the...
Chris Lovell, Gareth Jones, Steve R. Gunn, Klaus-P...
ANSS
2006
IEEE
14 years 2 days ago
iSimBioSys: A Discrete Event Simulation Platform for 'in silico' study of biological systems
With the availability of huge databases cataloguing the various molecular “parts” of complex biological systems, researchers from multiple disciplines have focused on developi...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
RECOMB
2009
Springer
14 years 6 months ago
Parameter Synthesis in Nonlinear Dynamical Systems: Application to Systems Biology
The dynamics of biological processes are often modeled as systems of nonlinear ordinary differential equations (ODE). An important feature of nonlinear ODEs is that seemingly minor...
Alexandre Donzé, Gilles Clermont, Axel Lega...