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» Role of Centrality in Network-Based Prioritization of Diseas...
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BMCBI
2010
115views more  BMCBI 2010»
13 years 4 months ago
Integration of multiple data sources to prioritize candidate genes using discounted rating system
Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
Yongjin Li, Jagdish Chandra Patra
DILS
2007
Springer
13 years 8 months ago
Accelerating Disease Gene Identification Through Integrated SNP Data Analysis
Information about small genetic variations in organisms, known as single nucleotide polymorphism (SNPs), is crucial to identify candidate genes that have a role in disease suscepti...
Paolo Missier, Suzanne M. Embury, Cornelia Hedeler...
RECOMB
2006
Springer
14 years 5 months ago
Algorithms to Distinguish the Role of Gene-Conversion from Single-Crossover Recombination in the Derivation of SNP Sequences in
Meiotic recombination is a fundamental biological event and one of the principal evolutionary forces responsible for shaping genetic variation within species. In addition to its fu...
Yun S. Song, Zhihong Ding, Dan Gusfield, Charles H...
NAR
2000
85views more  NAR 2000»
13 years 4 months ago
MitoNuc and MitoAln: two related databases of nuclear genes coding for mitochondrial proteins
Mitochondria, besides their central role in energy metabolism, have recently been found to be involved in a number of basic processes of cell life and to contribute to the pathoge...
Graziano Pesole, Carmela Gissi, Domenico Catalano,...