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BMCBI
2010
149views more  BMCBI 2010»
13 years 5 months ago
RuleMonkey: software for stochastic simulation of rule-based models
Background: The system-level dynamics of many molecular interactions, particularly protein-protein interactions, can be conveniently represented using reaction rules, which can be...
Joshua Colvin, Michael I. Monine, Ryan N. Gutenkun...
TCSB
2010
13 years 3 months ago
Rule-Based Modeling of Transcriptional Attenuation at the Tryptophan Operon
Transcriptional attenuation at E.coli’s tryptophan operon is a prime example of RNA-mediated gene regulation. In this paper, we present a discrete stochastic model for this pheno...
Céline Kuttler, Cédric Lhoussaine, M...
LICS
2010
IEEE
13 years 3 months ago
Abstracting the Differential Semantics of Rule-Based Models: Exact and Automated Model Reduction
ing the differential semantics of rule-based models: exact and automated model reduction (Invited Lecture) Vincent Danos∗§, J´erˆome Feret†, Walter Fontana‡, Russell Harme...
Vincent Danos, Jérôme Feret, Walter F...
SIMULATION
2010
96views more  SIMULATION 2010»
12 years 11 months ago
A Formal Framework for Stochastic Discrete Event System Specification Modeling and Simulation
Rodrigo Castro, Ernesto Kofman, Gabriel A. Wainer
BMCBI
2004
323views more  BMCBI 2004»
13 years 4 months ago
Biochemical Network Stochastic Simulator (BioNetS): software for stochastic modeling of biochemical networks
Background: Intrinsic fluctuations due to the stochastic nature of biochemical reactions can have large effects on the response of biochemical networks. This is particularly true ...
David Adalsteinsson, David McMillen, Timothy C. El...