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» Selecting Genomes for Reconstruction of Ancestral Genomes
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BMCBI
2008
138views more  BMCBI 2008»
13 years 5 months ago
Comparative analyses of bidirectional promoters in vertebrates
Background: Orthologous genes with deep phylogenetic histories are likely to retain similar regulatory features. In this report we utilize orthology assignments for pairs of genes...
Mary Qu Yang, James Taylor, Laura Elnitski
NAR
2000
117views more  NAR 2000»
13 years 5 months ago
The TIGR Gene Indices: reconstruction and representation of expressed gene sequences
Expressed sequence tags (ESTs) have provided a first glimpse of the collection of transcribed sequences in a variety of organisms. However, a careful analysis of this sequence dat...
John Quackenbush, Feng Liang, Ingeborg Holt, Geo P...
RECOMB
2008
Springer
14 years 6 months ago
Accurate Computation of Likelihoods in the Coalescent with Recombination Via Parsimony
Understanding the variation of recombination rates across a given genome is crucial for disease gene mapping and for detecting signatures of selection, to name just a couple of app...
Jotun Hein, Rune B. Lyngsø, Yun S. Song
RECOMB
2005
Springer
14 years 6 months ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
BMCBI
2007
124views more  BMCBI 2007»
13 years 5 months ago
BranchClust: a phylogenetic algorithm for selecting gene families
Background: Automated methods for assembling families of orthologous genes include those based on sequence similarity scores and those based on phylogenetic approaches. The first ...
Maria S. Poptsova, J. Peter Gogarten