12 search results - page 1 / 3 » Selecting Optimal Oligonucleotide Primers for Multiplex PCR |
ISMB
1997
13 years 6 months ago
1997
Weinvestigate the problemof designingefficient multiplex PCRfor medical applications. Weshowthat the problemis NP-completeby transformation to the Multiple Choice Matchingproblema...
BMCBI
2010
13 years 5 months ago
2010
Background: Multiplex PCR, defined as the simultaneous amplification of multiple regions of a DNA template or multiple DNA templates using more than one primer set (comprising a f...
BMCBI
2006
13 years 5 months ago
2006
Background: The design of oligonucleotides and PCR primers for studying large genomes is complicated by the redundancy of sequences. The eukaryotic genomes are particularly diffic...
BIOINFORMATICS
2007
13 years 5 months ago
2007
Primer approximation multiplex PCR (PAMP) is a new experimental protocol for efficiently assaying structural variation in genomes. PAMP is particularly suited to cancer genomes w...
BMCBI
2008
13 years 5 months ago
2008
Background: Polymerase chain reaction (PCR) is used in directed sequencing for the discovery of novel polymorphisms. As the first step in PCR directed sequencing, effective PCR pr...