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» Spotting effect in microarray experiments
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BIOINFORMATICS
2005
93views more  BIOINFORMATICS 2005»
13 years 5 months ago
Donuts, scratches and blanks: robust model-based segmentation of microarray images
Inner holes, artifacts and blank spots are common in microarray images, but current image analysis methods do not pay them enough attention. We propose a new robust model-based me...
Qunhua Li, Chris Fraley, Roger Eugene Bumgarner, K...
BIOINFORMATICS
2002
123views more  BIOINFORMATICS 2002»
13 years 5 months ago
Making sense of microarray data distributions
Motivation: Typical analysis of microarray data has focused on spot by spot comparisons within a single organism. Less analysis has been done on the comparison of the entire distr...
David C. Hoyle, Magnus Rattray, Ray Jupp, Andy Bra...
BIBE
2008
IEEE
150views Bioinformatics» more  BIBE 2008»
13 years 5 months ago
Automatic DNA microarray gridding based on Support Vector Machines
This paper presents a novel method for DNA microarray gridding based on Support Vector Machine (SVM) classifiers. It employs a set of soft-margin SVMs to estimate the lines of the ...
Dimitris G. Bariamis, Dimitris Maroulis, Dimitrios...
BIOINFORMATICS
2005
72views more  BIOINFORMATICS 2005»
13 years 5 months ago
Use of within-array replicate spots for assessing differential expression in microarray experiments
Motivation. Spotted arrays are often printed with probes in duplicate or triplicate, but current methods for assessing differential expression are not able to make full use of the...
Gordon K. Smyth, Joëlle Michaud, Hamish S. Sc...
RECOMB
2007
Springer
14 years 5 months ago
Design of Compact, Universal DNA Microarrays for Protein Binding Microarray Experiments
Our group has recently developed a compact, universal protein binding microarray (PBM) that can be used to determine the binding preferences of transcription factors (TFs) [1]. Thi...
Anthony A. Philippakis, Aaron M. Qureshi, Michael ...