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DIS
2008
Springer
13 years 6 months ago
Active Learning for High Throughput Screening
Abstract. An important task in many scientific and engineering disciplines is to set up experiments with the goal of finding the best instances (substances, compositions, designs) ...
Kurt De Grave, Jan Ramon, Luc De Raedt
BIOCOMP
2006
13 years 6 months ago
Evaluation of a Novel Metric for Quality Control in an RNA Interference High Throughput Screening Assay
The application of genome scale RNA interference (RNAi) relies on the development of high quality RNAi high throughput screening (HTS) assays. An important quality control (QC) ch...
Xiaohua Douglas Zhang, Amy S. Espeseth, Namjin Chu...
BMCBI
2008
82views more  BMCBI 2008»
13 years 4 months ago
Standardized high-throughput evaluation of cell-based compound screens
Background: High-throughput screening of pharmaceutical compound activity in tissue culture experiments requires time-consuming repeated analysis of the large amounts of data gene...
Peter Frommolt, Roman K. Thomas
CANDC
2005
ACM
13 years 4 months ago
Assessment of chemical libraries for their druggability
High throughput virtual screening is acknowledged as the initial means for identifying hit compounds that will be eventually transformed to leads or drug candidates. To improve qu...
Suzanne W. Sirois, George Hatzakis, Dongqing Wei, ...