The tertiary (3D) structure of a protein contains the essential information for understanding the biological function of the protein at the molecular and cellular levels. Traditio...
Manesh J. Shah, Sergei Passovets, Dongsup Kim, Kyl...
Loop closure in proteins requires computing the values of the inverse kinematics (IK) map for a backbone fragment with 2n 6 torsional degrees of freedom (dofs). It occurs in a va...
R. James Milgram, Guanfeng Liu, Jean-Claude Latomb...
Protein loop structure modeling is regarded as a mini protein folding problem with significant scientific importance. Efficiently sampling the loop conformation space is a key step...
Background: Since experimental determination of protein folding pathways remains difficult, computational techniques are often used to simulate protein folding. Most current techn...