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» Subtle Motif Discovery for Detection of DNA Regulatory Sites
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BMCBI
2007
247views more  BMCBI 2007»
13 years 6 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
ISMB
2000
13 years 7 months ago
Combinatorial Approaches to Finding Subtle Signals in DNA Sequences
Signal nding pattern discovery in unaligned DNA sequences is a fundamental problem in both computer science and molecular biology with important applications in locating regulator...
Pavel A. Pevzner, Sing-Hoi Sze
RECOMB
2001
Springer
14 years 6 months ago
Finding motifs using random projections
motif discovery problem abstracts the task of discovering short, conserved sites in genomic DNA. Pevzner and Sze recently described a precise combinatorial formulation of motif di...
Jeremy Buhler, Martin Tompa
BMCBI
2005
130views more  BMCBI 2005»
13 years 5 months ago
Some statistical properties of regulatory DNA sequences, and their use in predicting regulatory regions in the Drosophila genome
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
Irina I. Abnizova, Rene te Boekhorst, Klaudia Walt...
BMCBI
2006
136views more  BMCBI 2006»
13 years 6 months ago
EMD: an ensemble algorithm for discovering regulatory motifs in DNA sequences
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...
Jianjun Hu, Yifeng D. Yang, Daisuke Kihara