Although tremendous effort has been put into synthetic libraries, most drugs on the market are still 10 natural compounds or derivatives thereof. There are encyclopaedias of natur...
The immune system protects organisms from foreign proteins, peptide epitopes and a multitude of chemical compounds. Among these, haptens are small molecules, eliciting an immune r...
Background: The toxic effects of many simple organic compounds stem from their biotransformation to chemically reactive metabolites which bind covalently to cellular proteins. To ...
Robert P. Hanzlik, Yakov M. Koen, Bhargav Theertha...
During the development of methods for cancer diagnosis and treatment, a vast amount of information is generated. Novel cancer target proteins have been identified and many compoun...
Jessica Ahmed, Thomas Meinel, Mathias Dunkel, Manu...
A vast number of sweet tasting molecules are known, encompassing small compounds, carbohydrates, D-amino acids and large proteins. Carbohydrates play a particularly big role in hu...