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» TSEMA: interactive prediction of protein pairings between in...
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BMCBI
2005
130views more  BMCBI 2005»
13 years 5 months ago
Some statistical properties of regulatory DNA sequences, and their use in predicting regulatory regions in the Drosophila genome
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
Irina I. Abnizova, Rene te Boekhorst, Klaudia Walt...
NAR
2007
132views more  NAR 2007»
13 years 5 months ago
TRED: a transcriptional regulatory element database, new entries and other development
Transcriptional factors (TFs) and many of their target genes are involved in gene regulation at the level of transcription. To decipher gene regulatory networks (GRNs) we require ...
C. Jiang, Zhenyu Xuan, Fang Zhao, Michael Q. Zhang
BMCBI
2010
176views more  BMCBI 2010»
13 years 5 months ago
TargetSpy: a supervised machine learning approach for microRNA target prediction
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
Martin Sturm, Michael Hackenberg, David Langenberg...
BIOCOMP
2006
13 years 7 months ago
The Generalized Topological Overlap Matrix for Detecting Modules in Gene Networks
Systems biologic studies of gene and protein interaction networks have found that these networks are comprised of `modules' (groups of tightly interconnected nodes). Module i...
Andy M. Yip, Steve Horvath
BMCBI
2010
165views more  BMCBI 2010»
13 years 5 months ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...