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» The ASTRAL compendium for protein structure and sequence ana...
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ALMOB
2007
155views more  ALMOB 2007»
13 years 5 months ago
Finding coevolving amino acid residues using row and column weighting of mutual information and multi-dimensional amino acid rep
Background: Some amino acid residues functionally interact with each other. This interaction will result in an evolutionary co-variation between these residues – coevolution. Ou...
Rodrigo Gouveia-Oliveira, Anders Gorm Pedersen
DILS
2005
Springer
13 years 11 months ago
Information Integration and Knowledge Acquisition from Semantically Heterogeneous Biological Data Sources
Abstract. We present INDUS (Intelligent Data Understanding System), a federated, query-centric system for knowledge acquisition from autonomous, distributed, semantically heterogen...
Doina Caragea, Jyotishman Pathak, Jie Bao, Adrian ...
RECOMB
2006
Springer
14 years 5 months ago
A Study of Accessible Motifs and RNA Folding Complexity
mRNA molecules are folded in the cells and therefore many of their substrings may actually be inaccessible to protein and microRNA binding. The need to apply an accessability crite...
Ydo Wexler, Chaya Ben-Zaken Zilberstein, Michal Zi...
BMCBI
2006
195views more  BMCBI 2006»
13 years 5 months ago
CAFTAN: a tool for fast mapping, and quality assessment of cDNAs
Background: The German cDNA Consortium has been cloning full length cDNAs and continued with their exploitation in protein localization experiments and cellular assays. However, t...
Coral del Val, Vladimir Yurjevich Kuryshev, Karl-H...
BMCBI
2006
134views more  BMCBI 2006»
13 years 5 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...