Background: A central question in cancer biology is what changes cause a healthy cell to form a tumor. Gene expression data could provide insight into this question, but it is dif...
Background: The development of high-throughput laboratory techniques created a demand for computer-assisted result analysis tools. Many of these techniques return lists of genes w...
We propose a design theory that tackles dynamic complexity in the design for Information Infrastructures (IIs) defined as a shared, open, heterogeneous and evolving socio-technica...
Publicly-available data sets provide detailed and large-scale information on multiple types of molecular interaction networks in a number of model organisms. These multi-modal univ...