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» WeederH: an algorithm for finding conserved regulatory motif...
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BMCBI
2006
120views more  BMCBI 2006»
13 years 5 months ago
An improved distance measure between the expression profiles linking co-expression and co-regulation in mouse
Background: Many statistical algorithms combine microarray expression data and genome sequence data to identify transcription factor binding motifs in the low eukaryotic genomes. ...
Ryung S. Kim, Hongkai Ji, Wing Hung Wong
BMCBI
2008
108views more  BMCBI 2008»
13 years 5 months ago
An analysis of the positional distribution of DNA motifs in promoter regions and its biological relevance
Background: Motif finding algorithms have developed in their ability to use computationally efficient methods to detect patterns in biological sequences. However the posterior cla...
Ana C. Casimiro, Susana Vinga, Ana T. Freitas, Arl...
CIBCB
2005
IEEE
13 years 7 months ago
A Transcriptional Approach to Gene Clustering
— We present an integrative method for clustering coregulated genes and elucidating their underlying regulatory mechanisms. We use multi-state partition functions and thermodynam...
Ilias Tagkopoulos
BMCBI
2007
142views more  BMCBI 2007»
13 years 5 months ago
Improving model construction of profile HMMs for remote homology detection through structural alignment
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
Juliana S. Bernardes, Alberto M. R. Dávila,...
RECOMB
2001
Springer
14 years 5 months ago
Algorithms for phylogenetic footprinting
Phylogenetic footprinting is a comparative genomics approach for predicting transcription factor binding sites, where a set of orthologous regulatory regions are compared and short...
Mathieu Blanchette