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» Yeast Ancestral Genome Reconstructions: The Possibilities of...
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BMCBI
2005
102views more  BMCBI 2005»
13 years 6 months ago
Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computatio
Background: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription...
Emmitt R. Jolly, Chen-Shan Chin, Ira Herskowitz, H...
ISMB
2007
13 years 8 months ago
Polyploids, genome halving and phylogeny
Autopolyploidization and allopolyploidization events multiply the number of chromosomes and genomic content. Genome rearrangement phylogenetics requires that all genomes analyzed ...
David Sankoff, Chunfang Zheng, Qian Zhu
RECOMB
2002
Springer
14 years 6 months ago
Inferring Piecewise Ancestral History from Haploid Sequences
There has been considerable recent interest in the use of haplotype structure to aid in the design and analysis of case-control association studies searching for genetic predictors...
Russell Schwartz, Andrew G. Clark, Sorin Istrail
BMCBI
2007
153views more  BMCBI 2007»
13 years 6 months ago
Estimating genealogies from linked marker data: a Bayesian approach
Background: Answers to several fundamental questions in statistical genetics would ideally require knowledge of the ancestral pedigree and of the gene flow therein. A few examples...
Dario Gasbarra, Matti Pirinen, Mikko J. Sillanp&au...
BCB
2010
161views Bioinformatics» more  BCB 2010»
13 years 1 months ago
Genome-wide compatible SNP intervals and their properties
Recent studies suggest that the mammalian genomes can be subdivided in segments within which there is limited haplotype diversity. Understanding the distribution and structure of ...
Jeremy W. Wang, Kyle J. Moore, Qi Zhang, Fernando ...