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BIBM
2008
IEEE
137views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Exploring Alternative Splicing Features Using Support Vector Machines
Alternative splicing is a mechanism for generating different gene transcripts (called isoforms) from the same genomic sequence. Finding alternative splicing events experimentally ...
Jing Xia, Doina Caragea, Susan Brown
BIBM
2008
IEEE
134views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
New Approaches to Compare Phylogenetic Search Heuristics
We present new and novel insights into the behavior of two maximum parsimony heuristics for building evolutionary trees of different sizes. First, our results show that the heuris...
Seung-Jin Sul, Suzanne Matthews, Tiffani L. Willia...
BIBM
2008
IEEE
108views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Systematic Evaluation of Scaling Methods for Gene Expression Data
Even after an experimentally prepared gene expression data set has been pre-processed to account for variations in the microarray technology, there may be inconsistencies between ...
Gaurav Pandey, Lakshmi Naarayanan Ramakrishnan, Mi...
BIBM
2008
IEEE
110views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Genome Alignments Using MPI-LAGAN
We develop a parallel algorithm for a widely used whole genome alignment method called LAGAN. We use the MPI-based protocol to develop parallel solutions for two phases of the alg...
Ruinan Zhang, Huzefa Rangwala, George Karypis
BIBM
2008
IEEE
170views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Protein Sequence Motif Super-Rule-Tree (SRT) Structure Constructed by Hybrid Hierarchical K-Means Clustering Algorithm
— Protein sequence motifs information is crucial to the analysis of biologically significant regions. The conserved regions have the potential to determine the role of the protei...
Bernard Chen, Jieyue He, Stephen Pellicer, Yi Pan