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BIBM
2008
IEEE
111views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Estimating Regulatory Associations of Genomic Loci and Biological Pathways in Lymphoblastoid Cells
Genetical genomics has been established to study genetic variation of gene expression. It treats transcript expression as a quantitative trait and identifies putative regulatory l...
Jung Hoon Woo, Eunjee Lee, Sung-Bum Cho, Ju Han Ki...
BIBM
2008
IEEE
142views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Using Global Sequence Similarity to Enhance Biological Sequence Labeling
Identifying functionally important sites from biological sequences, formulated as a biological sequence labeling problem, has broad applications ranging from rational drug design ...
Cornelia Caragea, Jivko Sinapov, Drena Dobbs, Vasa...
BIBM
2008
IEEE
141views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Protein-Protein Interaction Network Alignment by Quantitative Simulation
We adapt a network simulation algorithm called quantitative simulation (QSim) for use in the alignment of biological networks. Unlike most network alignment methods, QSim finds l...
Perry Evans, Ted Sandler, Lyle H. Ungar
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
13 years 7 months ago
On the Role of Local Matching for Efficient Semi-supervised Protein Sequence Classification
Recent studies in protein sequence analysis have leveraged the power of unlabeled data. For example, the profile and mismatch neighborhood kernels have shown significant improveme...
Pavel P. Kuksa, Pai-Hsi Huang, Vladimir Pavlovic
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
13 years 5 months ago
Systems Biology via Redescription and Ontologies (III): Protein Classification Using Malaria Parasite's Temporal Transcriptomic
This paper addresses the protein classification problem, and explores how its accuracy can be improved by using information from time-course gene expression data. The methods are ...
Antonina Mitrofanova, Samantha Kleinberg, Jane Car...