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BIBM
2008
IEEE
105views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Energy Profile and Secondary Structure Impact shRNA Efficacy
Many characteristics of functional synthetic siRNAs have been identified. Our three-phase algorithm was developed to design siRNA on a wholegenome scale based on these characteris...
Hong Zhou, Xiao Zeng
BIBM
2008
IEEE
107views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
A Functional Network of Yeast Genes Using Gene Ontology Information
In the post-genomic era, the organization of genes into networks has played an important role in characterizing the functions of individual genes and the interplay between them. I...
Erliang Zeng, Giri Narasimhan, Lisa Schneper, Kala...
BIBM
2008
IEEE
112views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Fast Alignments of Metabolic Networks
Network alignments are extensively used for comparing, exploring, and predicting biological networks. Existing alignment tools are mostly based on isomorphic and homeomorphic embe...
Qiong Cheng, Piotr Berman, Robert W. Harrison, Ale...
BIBM
2008
IEEE
212views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Analysis of Multiplex Gene Expression Maps Obtained by Voxelation
Background: Gene expression signatures in the mammalian brain hold the key to understanding neural development and neurological disease. Researchers have previously used voxelatio...
Li An, Hongbo Xie, Mark H. Chin, Zoran Obradovic, ...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
13 years 11 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...