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WABI
2007
Springer
14 years 7 days ago
Shotgun Protein Sequencing
Although snake venom proteins have been proven instrumental in the design of blood clotting and cytostatic breast cancer drugs, the main method in use to sequence these unknown pr...
Pavel A. Pevzner
WABI
2007
Springer
102views Bioinformatics» more  WABI 2007»
14 years 7 days ago
Homology Search with Fragmented Nucleic Acid Sequence Patterns
The comprehensive annotation of non-coding RNAs in newly sequenced genomes is still a largely unsolved problem because many functional RNAs exhibit not only poorly conserved sequen...
Axel Mosig, Julian J.-L. Chen, Peter F. Stadler
AB
2007
Springer
13 years 10 months ago
Efficient Haplotype Inference with Pseudo-boolean Optimization
Abstract. Haplotype inference from genotype data is a key computational problem in bioinformatics, since retrieving directly haplotype information from DNA samples is not feasible ...
Ana Graça, João Marques-Silva, In&ec...
EVOW
2007
Springer
13 years 10 months ago
Dinucleotide Step Parameterization of Pre-miRNAs Using Multi-objective Evolutionary Algorithms
MicroRNAs (miRNAs) form a large functional family of small noncoding RNAs and play an important role as posttranscriptional regulators, by repressing the translation of mRNAs. Rece...
Jin-Wu Nam, In-Hee Lee, Kyu Baek Hwang, Seong-Bae ...
GECCO
2007
Springer
258views Optimization» more  GECCO 2007»
13 years 10 months ago
TFBS identification by position- and consensus-led genetic algorithm with local filtering
Identification of Transcription Factor Binding Site (TFBS) motifs in multiple DNA upstream sequences is important in understanding the mechanism of gene regulation. This identific...
Tak-Ming Chan, Kwong-Sak Leung, Kin-Hong Lee