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ISMB
1997
13 years 7 months ago
Functional Prediction of B. subtilis Genes from Their Regulatory Sequences
In bacterial cells, gene expression is regulated by multiple sigma factors, each of which has its promoter specificity, according to their conditions. Thus, if we can discriminate...
Tetsushi Yada, Yasushi Totoki, Takahiro Ishii, Ken...
ISMB
1997
13 years 7 months ago
Bayesian Adaptive Alignment and Inference
Sequencealignmentwithoutthe specification of gap penaltiesor a scoringmatrixis attainedbyusing Bayesianinferenceanda recursivealgorithm.Thisprocedure’srecursivealgorithmsumsover...
Jun Zhu, Jun S. Liu, Charles E. Lawrence
ISMB
1997
13 years 7 months ago
Hierarchical Protein Structure Superposition Using Both Secondary Structure and Atomic Representations
The structural comparison of proteins has become increasingly important as a means to identify protein motifs and fold families. In this paper we present a new algorithm for the c...
Amit Pal Singh, Douglas L. Brutlag
ISMB
1997
13 years 7 months ago
Adding Semantics to Genome Databases: Towards an Ontology for Molecular Biology
Molecular biology has a communicationproblem. There are manydatabases using their ownlabels and categories for storing data objects and someusing identical labels andcategories bu...
Steffen Schulze-Kremer
ISMB
1997
13 years 7 months ago
A Fast Heuristic Algorithm for a Probe Mapping Problem
Anewheuristic algorithm is presented for mapping probes to locations along the genome,given noisy pairwise distance data as input. Themodel consideredis quite general: Theinput co...
Brendan Mumey