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RECOMB
2005
Springer
14 years 5 months ago
A Partial Solution to the C-Value Paradox
In the half-century since the C-value paradox (the apparent lack of correlation between organismal genome size and morphological complexity) was described, there have been no expli...
Jeffrey M. Marcus
RECOMB
2005
Springer
14 years 5 months ago
A Practical Approach to Significance Assessment in Alignment with Gaps
Abstract. Current numerical methods for assessing the statistical significance of local alignments with gaps are time consuming. Analytical solutions thus far have been limited to ...
Nicholas Chia, Ralf Bundschuh
RECOMB
2005
Springer
14 years 5 months ago
The Incompatible Desiderata of Gene Cluster Properties
Abstract. There is widespread interest in comparative genomics in determining if historically and/or functionally related genes are spatially clustered in the genome, and whether t...
Rose Hoberman, Dannie Durand
RECOMB
2005
Springer
14 years 5 months ago
Stability of Rearrangement Measures in the Comparison of Genome Sequences
We present data-analytic and statistical tools for studying rates of rearrangement of whole genomes and to assess the stability of these methods with changes in the level of resol...
David Sankoff, Matthew Mazowita
RECOMB
2005
Springer
14 years 5 months ago
Reversals of Fortune
Abstract. The objective function of the genome rearrangement problems allows the integration of other genome-level problems so that they may be solved simultaneously. Three example...
David Sankoff, Chunfang Zheng, Aleksander Lenert