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RECOMB
2006
Springer
14 years 5 months ago
Permutation Filtering: A Novel Concept for Significance Analysis of Large-Scale Genomic Data
Permutation of class labels is a common approach to build null distributions for significance analyis of microarray data. It is assumed to produce random score distributions, which...
Stefanie Scheid, Rainer Spang
RECOMB
2006
Springer
14 years 5 months ago
Detecting the Dependent Evolution of Biosequences
Abstract. A probabilistic graphical model is developed in order to detect the dependent evolution between different sites in biological sequences. Given a multiple sequence alignme...
Jeremy Darot, Chen-Hsiang Yeang, David Haussler
RECOMB
2006
Springer
14 years 5 months ago
Sorting by Weighted Reversals, Transpositions, and Inverted Transpositions
Abstract. During evolution, genomes are subject to genome rearrangements that alter the ordering and orientation of genes on the chromosomes. If a genome consists of a single chrom...
Martin Bader, Enno Ohlebusch
RECOMB
2006
Springer
14 years 5 months ago
Evolution of Tandemly Repeated Sequences Through Duplication and Inversion
Abstract. Given a phylogenetic tree T for a family of tandemly repeated genes and their signed order O on the chromosome, we aim to find the minimum number of inversions compatible...
Denis Bertrand, Mathieu Lajoie, Nadia El-Mabrouk, ...
RECOMB
2006
Springer
14 years 5 months ago
Sorting by Translocations Via Reversals Theory
Abstract. The understanding of genome rearrangements is an important endeavor in comparative genomics. A major computational problem in this field is finding a shortest sequence of...
Michal Ozery-Flato, Ron Shamir