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NIPS
2004
10 years 4 months ago
Discrete profile alignment via constrained information bottleneck
Amino acid profiles, which capture position-specific mutation probabilities, are a richer encoding of biological sequences than the individual sequences themselves. However, profi...
Sean O'Rourke, Gal Chechik, Robin Friedman, Eleaza...
APBC
2004
10 years 4 months ago
Recognition Sequences in the Restriction Endonucleases
The nature of specific protein-nucleic acid interaction between restriction endonucleases (RE) and their recognition sequences (RS) was studied by bioinformatics methods. It was f...
Jan C. Biro, Josephine M. K. Biro
CMSB
2008
Springer
10 years 4 months ago
Stochastic Analysis of Amino Acid Substitution in Protein Synthesis
Abstract. We present a formal analysis of amino acid replacement during mRNA translation. Building on an abstract stochastic model of arrival of tRNAs and their processing at the r...
Dragan Bosnacki, Huub M. M. ten Eikelder, M. N. St...
AUSDM
2006
Springer
144views Data Mining» more  AUSDM 2006»
10 years 6 months ago
Mining Quantitative Association Rules in Protein Sequences
Abstract. Lot of research has gone into understanding the composition and nature of proteins, still many things remain to be understood satisfactorily. It is now generally believed...
Nitin Gupta, Nitin Mangal, Kamal Tiwari, Pabitra M...
CSB
2004
IEEE
110views Bioinformatics» more  CSB 2004»
10 years 6 months ago
SPIDER: Software for Protein Identification from Sequence Tags with De Novo Sequencing Error
For the identification of novel proteins using MS/MS, de novo sequencing software computes one or several possible amino acid sequences (called sequence tags) for each MS/MS spect...
Yonghua Han, Bin Ma, Kaizhong Zhang
CSB
2003
IEEE
10 years 8 months ago
A New Similarity Measure among Protein Sequences
Protein sequence analysis is an important tool to decode the logic of life. One of the most important similarity measures in this area is the edit distance between amino acids of ...
Kuen-Pin Wu, Hsin-Nan Lin, Ting-Yi Sung, Wen-Lian ...
WABI
2004
Springer
10 years 8 months ago
A Polynomial-Time Algorithm for the Matching of Crossing Contact-Map Patterns
Abstract. Contact maps are a model to capture the core information in the structure of biological molecules, e.g., proteins. A contact map consists of an ordered set ¡ of elements...
Jens Gramm
IJCNN
2006
IEEE
10 years 8 months ago
Comparing Kernels for Predicting Protein Binding Sites from Amino Acid Sequence
— The ability to identify protein binding sites and to detect specific amino acid residues that contribute to the specificity and affinity of protein interactions has importan...
Feihong Wu
ECAL
2007
Springer
10 years 8 months ago
Folding Protein-Like Structures with Open L-Systems
Abstract. Proteins, under native conditions, fold to specific 3D structures according to their 1D amino acid sequence, which in turn is defined by the genetic code. The specific...
Gemma B. Danks, Susan Stepney, Leo S. D. Caves
BIRD
2007
Springer
117views Bioinformatics» more  BIRD 2007»
10 years 8 months ago
Enhancing Protein Disorder Detection by Refined Secondary Structure Prediction
More and more proteins have been observed to display functions through intrinsic disorder. Such structurally flexible regions are shown to play important roles in biological proces...
Chung-Tsai Su, Tong-Ming Hsu, Chien-Yu Chen, Yu-Ye...
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