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BCB
2010
156views Bioinformatics» more  BCB 2010»
12 years 12 months ago
RepFrag: a graph based method for finding repeats and transposons from fragmented genomes
Growing sequencing and assembly efforts have been met by the advances in high throughput machines. However, the presence of massive amounts of repeats and transposons complicates ...
Nirmalya Bandyopadhyay, A. Mark Settles, Tamer Kah...
BCB
2010
140views Bioinformatics» more  BCB 2010»
12 years 12 months ago
Guiding belief propagation using domain knowledge for protein-structure determination
A major bottleneck in high-throughput protein crystallography is producing protein-structure models from an electrondensity map. In previous work, we developed Acmi, a probabilist...
Ameet Soni, Craig A. Bingman, Jude W. Shavlik
BCB
2010
156views Bioinformatics» more  BCB 2010»
12 years 12 months ago
Accelerating HMMER on GPUs by implementing hybrid data and task parallelism
Many biologically motivated problems are expressed as dynamic programming recurrences and are difficult to parallelize due to the intrinsic data dependencies in their algorithms. ...
Narayan Ganesan, Roger D. Chamberlain, Jeremy Buhl...
BCB
2010
126views Bioinformatics» more  BCB 2010»
12 years 12 months ago
Functional similarities of reaction sets in metabolic pathways
Analyzing metabolic pathways by means of their steady states has proven to be accurate and efficient for practical purposes. The models such as elementary flux modes (EFMs) and ex...
Ferhat Ay, Tamer Kahveci
BCB
2010
125views Bioinformatics» more  BCB 2010»
12 years 12 months ago
Protein structure alignment using elastic shape analysis
In this paper we present a method for flexible protein structure alignment based on elastic shape analysis of backbones, in a manner that can incorporate different characteristics...
Wei Liu, Anuj Srivastava, Jinfeng Zhang