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ACSW
2006
13 years 6 months ago
Toward building grid applications in bioinformatics
In silico bioinformatics experiments involve integration of and access to computational tools and biological databases. The emerging grid computing technologies enable bioinformat...
Xiujun Gong, Kensuke Nakamura, Kei Yura, Nobuhiro ...
WOB
2008
101views Bioinformatics» more  WOB 2008»
13 years 6 months ago
Top-Down Hierarchical Ensembles of Classifiers for Predicting G-Protein-Coupled-Receptor Functions
Abstract. Despite the recent advances in Molecular Biology, the function of a large amount of proteins is still unknown. An approach that can be used in the prediction of a protein...
Eduardo P. Costa, Ana Carolina Lorena, André...
WOB
2008
128views Bioinformatics» more  WOB 2008»
13 years 6 months ago
Tests for Gene Clusters Satisfying the Generalized Adjacency Criterion
Abstract. We study a parametrized definition of gene clusters that permits control over the trade-off between increasing gene content versus conserving gene order within a cluster....
Ximing Xu, David Sankoff
BIOCOMP
2008
13 years 6 months ago
Prediction of Protein Function Using Graph Container and Message Passing
We introduce a novel parameter called container flux, which is used to measure the information sharing capacity between two distinct nodes in a graph. Other useful information, bot...
Hongbo Zhou, Qiang Shawn Cheng, Mehdi Zargham
BIOCOMP
2008
13 years 6 months ago
Stochastic Simulation Algorithms for Chemical Reactions
Tae-Hyuk Ahn, Yang Cao, Layne T. Watson
BIOCOMP
2008
13 years 6 months ago
Inverse protein folding in 3D hexagonal prism lattice under HP model
Alireza Hadj Khodabakhshi, Ján Manuch, Aras...
BIOCOMP
2008
13 years 6 months ago
Analysis of Microarray Titration Experiments
In this paper we introduce a novel approach for the analysis of microarray titration experiments. The test introduced here can be used more generally for drug-dosage effect or time...
Ionut Bebu, Françoise Seillier-Moiseiwitsch...
BIOCOMP
2008
13 years 6 months ago
Analysis of Protein-Ligand Interactions Using Localized Stereochemical Features
Computational analyses of protein structure-function relationships have traditionally been based on sequence homology, fold family analysis and 3D motifs/templates. Previous struct...
Reetal Pai, James C. Sacchettini, Thomas R. Ioerge...
BIOCOMP
2008
13 years 6 months ago
Discoveries in shRNA Design
-- To successfully apply RNAi, the very first step is to design functional siRNA or shRNA sequences targeting specific genes. Many characteristics of functional synthetic siRNAs ha...
Hong Zhou, Xiao Zeng, Joseph Manthey
BIOCOMP
2008
13 years 6 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...