BMCBI
2005
13 years 4 months ago
2005
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
BMCBI
2005
13 years 4 months ago
2005
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
BMCBI
2005
13 years 4 months ago
2005
Background: The ability to distinguish between genes and proteins is essential for understanding biological text. Support Vector Machines (SVMs) have been proven to be very effici...
BMCBI
2005
13 years 4 months ago
2005
Abstract. Taxonomy provides one of the most powerful ways to navigate sequence data bases but currently, users are forced to formulate queries according to a single taxonomic class...
BMCBI
2005
13 years 4 months ago
2005
BMCBI
2005
13 years 4 months ago
2005
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
BMCBI
2005
13 years 4 months ago
2005
Background: Although DNA microarray technologies are very powerful for the simultaneous quantitative characterization of thousands of genes, the quality of the obtained experiment...
BMCBI
2005
13 years 4 months ago
2005
Background: Post-translational modification by Small Ubiquitin-like Modifiers (SUMO) has been implicated in protein targeting, in the maintenance of genomic integrity and in trans...
BMCBI
2005
13 years 4 months ago
2005
Background: Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved se...
BMCBI
2005
13 years 4 months ago
2005
Background: During the last few years, DNA sequence analysis has become one of the primary means of taxonomic identification of species, particularly so for species that are minut...