BMCBI
2008
13 years 4 months ago
2008
BMCBI
2008
13 years 4 months ago
2008
Background: Missing values frequently pose problems in gene expression microarray experiments as they can hinder downstream analysis of the datasets. While several missing value i...
BMCBI
2008
13 years 4 months ago
2008
Background: Single nucleotide polymorphisms (SNPs) are the most common genetic variations in the human genome and are useful as genomic markers. Oligonucleotide SNP microarrays ha...
BMCBI
2008
13 years 4 months ago
2008
Background: Despite considerable efforts within the microarray community for standardising data format, content and description, microarray technologies present major challenges i...
BMCBI
2008
13 years 4 months ago
2008
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
BMCBI
2008
13 years 4 months ago
2008
Background: Outer membrane proteins (OMPs) perform diverse functional roles in Gramnegative bacteria. Identification of outer membrane proteins is an important task. Results: This...
BMCBI
2008
13 years 4 months ago
2008
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
BMCBI
2008
13 years 4 months ago
2008
Background: Virtual or in silico ligand screening combined with other computational methods is one of the most promising methods to search for new lead compounds, thereby greatly ...
BMCBI
2008
13 years 4 months ago
2008
Background: It is an important pre-processing step to accurately estimate missing values in microarray data, because complete datasets are required in numerous expression profile ...
BMCBI
2008
13 years 4 months ago
2008
Background: High-throughput genotyping technology has enabled cost effective typing of thousands of individuals in hundred of thousands of markers for use in genome wide studies. ...