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CIBCB
2005
IEEE
10 years 3 months ago
Pathway Analyst--Automated Metabolic Pathway Prediction
—Metabolic pathways are crucial to our understanding of biology. The speed at which new organisms are being sequenced is outstripping our ability to experimentally determine thei...
Luca Pireddu, Brett Poulin, Duane Szafron, Paul Lu...
CIBCB
2005
IEEE
10 years 3 months ago
A Transcriptional Approach to Gene Clustering
— We present an integrative method for clustering coregulated genes and elucidating their underlying regulatory mechanisms. We use multi-state partition functions and thermodynam...
Ilias Tagkopoulos
CIBCB
2005
IEEE
10 years 3 months ago
Neuro-fuzzy Prediction of Biological Activity and Rule Extraction for HIV-1 Protease Inhibitors
— A fuzzy neural network (FNN) and multiple linear regression (MLR) were used to predict biological activities of 26 newly designed HIV-1 protease potential inhibitory compounds....
Razvan Andonie, Levente Fabry-Asztalos, Catharine ...
CIBCB
2005
IEEE
10 years 7 months ago
Cooperative Rec-I-DCM3: A Population-Based Approach for Reconstructing Phylogenies
Abstract— In this paper, we study the use of cooperation as a technique for designing faster algorithms for reconstructing phylogenetic trees. Our focus is on the use of cooperat...
Tiffani Williams, Marc Smith
CIBCB
2005
IEEE
10 years 7 months ago
Feedback Memetic Algorithms for Modeling Gene Regulatory Networks
— In this paper we address the problem of finding gene regulatory networks from experimental DNA microarray data. We focus on the evaluation of the performance of memetic algori...
Christian Spieth, Felix Streichert, Jochen Supper,...
CIBCB
2005
IEEE
10 years 7 months ago
Predicting Single Genes Related to Immune-Relevant Processes
— In this paper we address the problem of predicting gene activities by finding gene regulatory dependencies in experimental DNA microarray data. Only few approaches to infer th...
Christian Spieth, Felix Streichert, Nora Speer, Ch...
CIBCB
2005
IEEE
10 years 7 months ago
Functional Distances for Genes Based on GO Feature Maps and their Application to Clustering
— With the invention of high throughput methods, researchers are capable of producing large amounts of biological data. During the analysis of such data, the need for a functiona...
Nora Speer, Holger Fröhlich, Christian Spieth...
CIBCB
2005
IEEE
10 years 7 months ago
Artificial Neural Network Analysis of DNA Microarray-based Prostate Cancer Recurrence
— DNA microarray-based gene expression profiles have been established for a variety of adult cancers. This paper addresses application of an artificial neural network (ANN) wit...
Leif E. Peterson, Mustafa Ozen, Halime Erdem, Andr...
CIBCB
2005
IEEE
10 years 7 months ago
Two-Phase EA/k-NN for Feature Selection and Classification in Cancer Microarray Datasets
Efficient and reliable methods that can find a small sample of informative genes amongst thousands are of great importance. In this area, much research is investigating the combina...
Thorhildur Juliusdottir, David Corne, Ed Keedwell,...
CIBCB
2005
IEEE
10 years 7 months ago
Feature Selection for Microarray Data Using Least Squares SVM and Particle Swarm Optimization
Feature selection is an important preprocessing technique for many pattern recognition problems. When the number of features is very large while the number of samples is relatively...
E. Ke Tang, Ponnuthurai N. Suganthan, Xin Yao
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