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CIBCB
2009
IEEE
13 years 6 months ago
Steady-state analysis of genetic regulatory networks modeled by nonlinear ordinary differential equations
Although Ordinary Differential Equations (ODEs) have been used to model Genetic Regulatory Networks (GRNs) in many previous works, their steady-state behaviors are not well studied...
Haixin Wang, Lijun Qian, Edward R. Dougherty
CIBCB
2009
IEEE
13 years 6 months ago
Improved prediction of trans-membrane spans in proteins using an artificial neural network
Tools for the identification of trans-membrane spans from the protein sequence are widely used in the experimental community. Computational structural biology seeks to increase the...
Julia Koehler, Ralf Mueller, Jens Meiler
ISMB
1993
13 years 6 months ago
Transmembrane Segment Prediction from Protein Sequence Data
Weconsider tile automatedidentification of transmembrane domains in membrane protein sequences. 324 proteins (containing 1585 segrrmnts) werc examined, representing every protein ...
Sholom M. Weiss, Dawn M. Cohen, Nitin Indurkhya
ISMB
1993
13 years 6 months ago
Pattern Discovery in Gene Regulation: Designing an Analysis Environment
Interactions that determinecellular fate are exceedingly complex, can take place at different levels of gene regulation and involve a large numberof components(such as genes, prot...
Stella Veretnik, Bruce R. Schatz
ISMB
1993
13 years 6 months ago
Building Large Knowledge Bases in Molecular Biology
Olivier Schmeltzer, Claudine Médigue, P. Uv...
ISMB
1993
13 years 6 months ago
Computationally Efficient Cluster Representation in Molecular Sequence Megaclassification
Molecular sequence megaclassification is a technique for automated protein sequence analysis and annotation. Implementation of the method has been limited by the need to store and...
David J. States, Nomi L. Harris, Lawrence Hunter
ISMB
1993
13 years 6 months ago
A Service-Oriented Information Sources Database for the Biological Sciences
Researchersin the biological sciencesrequire access to a variety of information sources locatedin variousplacesondifferent computer networks.In order to satisfy the information ne...
Gordon K. Springer, Timothy B. Patrick
ISMB
1993
13 years 6 months ago
Minimizing Complexity in Cellular Automata Models of Self-Replication
Understanding self-replication from an information processing perspective is important because, amongother things, it can shed light on molecular mechanismsof biological reproduct...
James A. Reggia, Hui-Hsien Chou, Steven L. Armentr...