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CORR
2010
Springer
135views Education» more  CORR 2010»
13 years 4 months ago
Optimal Design of a Molecular Recognizer: Molecular Recognition as a Bayesian Signal Detection Problem
Numerous biological functions--such as enzymatic catalysis, the immune response system, and the DNA-protein regulatory network--rely on the ability of molecules to specifically rec...
Yonatan Savir, Tsvi Tlusty
CORR
2010
Springer
105views Education» more  CORR 2010»
13 years 4 months ago
Molecular Recognition as an Information Channel: The Role of Conformational Changes
Molecular recognition, which is essential in processing information in biological systems, takes place in a crowded noisy biochemical environment and requires the recognition of a ...
Yonatan Savir, Tsvi Tlusty
BMCBI
2008
124views more  BMCBI 2008»
13 years 4 months ago
Alignment of protein structures in the presence of domain motions
Background: Structural alignment is an important step in protein comparison. Well-established methods exist for solving this problem under the assumption that the structures under...
Roberto Mosca, Barbara Brannetti, Thomas R. Schnei...
BMCBI
2010
133views more  BMCBI 2010»
13 years 4 months ago
Integrated prediction of one-dimensional structural features and their relationships with conformational flexibility in helical
Background: Many structural properties such as solvent accessibility, dihedral angles and helix-helix contacts can be assigned to each residue in a membrane protein. Independent s...
Shandar Ahmad, Yumlembam Hemjit Singh, Yogesh Paud...
WABI
2005
Springer
13 years 10 months ago
Improved Maintenance of Molecular Surfaces Using Dynamic Graph Connectivity
We present recent developments in efficiently maintaining the boundary and surface area of protein molecules as they undergo conformational changes. As the method that we devised k...
Eran Eyal, Dan Halperin
RECOMB
2006
Springer
14 years 4 months ago
Simulating Protein Motions with Rigidity Analysis
Abstract. Protein motions, ranging from molecular flexibility to largescale conformational change, play an essential role in many biochemical processes. Despite the explosion in ou...
Shawna L. Thomas, Xinyu Tang, Lydia Tapia, Nancy M...
RECOMB
2007
Springer
14 years 4 months ago
Protein Conformational Flexibility Analysis with Noisy Data
Abstract. Protein conformational changes play a critical role in biological functions such as ligand-protein and protein-protein interactions. Due to the noise in structural data, ...
Anshul Nigham, David Hsu