BMCBI
2006
13 years 4 months ago
2006
Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
BMCBI
2006
13 years 4 months ago
2006
Background: Gene expression profiling has become a useful biological resource in recent years, and it plays an important role in a broad range of areas in biology. The raw gene ex...
BMCBI
2006
13 years 4 months ago
2006
Background: Understanding the relationship between gene expression changes, enzyme activity shifts, and the corresponding physiological adaptive response of organisms to environme...
BMCBI
2006
13 years 4 months ago
2006
Background: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. He...
BMCBI
2006
13 years 4 months ago
2006
Background: Clustering of gene expression patterns is a well-studied technique for elucidating trends across large numbers of transcripts and for identifying likely co-regulated g...
BMCBI
2006
13 years 4 months ago
2006
Background: Serial Analysis of Gene Expressions (SAGE) produces gene expression measurements on a discrete scale, due to the finite number of molecules in the sample. This means t...
BMCBI
2006
13 years 4 months ago
2006
Background: Modeling of cis-elements or regulatory motifs in promoter (upstream) regions of genes is a challenging computational problem. In this work, set of regulatory motifs si...
BMCBI
2006
13 years 4 months ago
2006
Background: Short oligonucleotide arrays for transcript profiling have been available for several years. Generally, raw data from these arrays are analysed with the aid of the Mic...
BMCBI
2006
13 years 4 months ago
2006
Background: Gene selection is an important step when building predictors of disease state based on gene expression data. Gene selection generally improves performance and identifi...
BMCBI
2006
13 years 4 months ago
2006
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...