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BMCBI
2007
144views more  BMCBI 2007»
13 years 5 months ago
Spectral estimation in unevenly sampled space of periodically expressed microarray time series data
Background: Periodogram analysis of time-series is widespread in biology. A new challenge for analyzing the microarray time series data is to identify genes that are periodically ...
Alan Wee-Chung Liew, Jun Xian, Shuanhu Wu, David K...
BMCBI
2007
163views more  BMCBI 2007»
13 years 5 months ago
Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approac
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Carmen Pin, Mark Reuter
BMCBI
2007
128views more  BMCBI 2007»
13 years 5 months ago
Combining classifiers to predict gene function in Arabidopsis thaliana using large-scale gene expression measurements
Background: Arabidopsis thaliana is the model species of current plant genomic research with a genome size of 125 Mb and approximately 28,000 genes. The function of half of these ...
Hui Lan, Rachel Carson, Nicholas J. Provart, Antho...
CSDA
2006
81views more  CSDA 2006»
13 years 5 months ago
Flexible temporal expression profile modelling using the Gaussian process
Time course gene expression experiments have proved valuable in a variety of biological studies [e.g., Chuang, Y., Chen, Y., Gadisetti, V., et al., 2002. Gene expression after tre...
Ming Yuan
BMCBI
2006
87views more  BMCBI 2006»
13 years 5 months ago
Computational expression deconvolution in a complex mammalian organ
Background: Microarray expression profiling has been widely used to identify differentially expressed genes in complex cellular systems. However, while such methods can be used to...
Min Wang, Stephen R. Master, Lewis A. Chodosh
BMCBI
2006
82views more  BMCBI 2006»
13 years 5 months ago
Prediction of a key role of motifs binding E2F and NR2F in down-regulation of numerous genes during the development of the mouse
Background: We previously demonstrated that gene expression profiles during neuronal differentiation in vitro and hippocampal development in vivo were very similar, due to a conse...
Michal Dabrowski, Stein Aerts, Bozena Kaminska
BMCBI
2006
103views more  BMCBI 2006»
13 years 5 months ago
Improving missing value imputation of microarray data by using spot quality weights
Background: Microarray technology has become popular for gene expression profiling, and many analysis tools have been developed for data interpretation. Most of these tools requir...
Peter Johansson, Jari Häkkinen
BMCBI
2006
155views more  BMCBI 2006»
13 years 5 months ago
Analysis of promoter regions of co-expressed genes identified by microarray analysis
Background: The use of global gene expression profiling to identify sets of genes with similar expression patterns is rapidly becoming a widespread approach for understanding biol...
Srinivas Veerla, Mattias Höglund
BMCBI
2006
85views more  BMCBI 2006»
13 years 5 months ago
On the statistical assessment of classifiers using DNA microarray data
Background: In this paper we present a method for the statistical assessment of cancer predictors which make use of gene expression profiles. The methodology is applied to a new d...
Nicola Ancona, Rosalia Maglietta, Ada Piepoli, Ann...
BMCBI
2006
88views more  BMCBI 2006»
13 years 5 months ago
Effect of various normalization methods on Applied Biosystems expression array system data
Background: DNA microarray technology provides a powerful tool for characterizing gene expression on a genome scale. While the technology has been widely used in discovery-based m...
Catalin C. Barbacioru, Yulei Wang, Roger D. Canale...