BIOINFORMATICS
2005
13 years 4 months ago
2005
Motivation: Genetic analysis of HIV-1 is important not only for vaccine development, but also to guide treatment strategies, track the emergence of new viral variants and ensure t...
BMCBI
2010
13 years 4 months ago
2010
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
BMCBI
2010
13 years 4 months ago
2010
Background: Human Immunodeficiency Virus type 1 (HIV-1), the causative agent of Acquired Immune Deficiency Syndrome (AIDS), exhibits very high genetic diversity with different var...
APBC
2004
13 years 6 months ago
2004
Mutation in HIV-1 is extremely rapid, a consequence of a low-fidelity viral reverse transcription process. The envelope gene has been shown to accumulate substitutions at a rate o...
GECCO
2005
Springer
13 years 10 months ago
2005
Springer
Researchers of HIV-1 are today, still unable to determine exactly the biological mechanisms that cause AIDS. Various mechanisms have been hypothesized and their existences have be...