JCB
2008
13 years 3 months ago
2008
Controlled intra-nuclear organisation of proteins is critical for sustaining correct function of the cell. Proteins and RNA are transported by passive diffusion and associate with...
JCB
2008
13 years 4 months ago
2008
A centromere is a special region in the chromosome that plays a vital role during cell division. Every new chromosome created by a genome rearrangement event must have a centromer...
JCB
2006
13 years 4 months ago
2006
Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e., segmentation con...
JCB
2006
13 years 4 months ago
2006
Genome-wide microarray designs containing millions to hundreds of millions of probes are available for a variety of mammals, including mouse and human. These genome tiling arrays ...
JCB
2006
13 years 4 months ago
2006
JCB
2006
13 years 4 months ago
2006
Protein
JCB
2006
13 years 4 months ago
2006
Recently a new algorithm for reverse engineering of biochemical networks was developed by Laubenbacher and Stigler. It is based on methods from computational algebra and finds mos...
JCB
2006
13 years 4 months ago
2006
JCB
2006
13 years 4 months ago
2006
The task of finding saddle points on potential energy surfaces plays a crucial role in understanding the dynamics of a micromolecule as well as in studying the folding pathways of...
JCB
2006
13 years 4 months ago
2006
Following Zuker (1986), a saturated secondary structure for a given RNA sequence is a secondary structure such that no base pair can be added without violating the definition of s...