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220views Database» more  ICDE 2011»
11 years 3 months ago
Generating test data for killing SQL mutants: A constraint-based approach
—Complex SQL queries are widely used today, but it is rather difficult to check if a complex query has been written correctly. Formal verification based on comparing a specifi...
Shetal Shah, S. Sudarshan, Suhas Kajbaje, Sandeep ...
11 years 6 months ago
Mutational analysis in RNAs: comparing programs for RNA deleterious mutation prediction
Programs for RNA mutational analysis that are structure-based and rely on secondary structure prediction have been developed and expanded in the past several years. They can be us...
Danny Barash, Alexander Churkin
126views more  BMCBI 2010»
11 years 9 months ago
PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
Gürkan Bebek, Vishal Patel, Mark R. Chance
70views more  NAR 1998»
11 years 11 months ago
Haemophilia B: database of point mutations and short additions and deletions--eighth edition
The eighth edition of the haemophilia B database ( ) lists in an easily accessible form all known factor IX mutations due to small ch...
F. Giannelli, P. M. Green, S. S. Sommer, M.-C. Poo...
107views more  NAR 1998»
11 years 11 months ago
Marfan Database (third edition): new mutations and new routines for the software
The Marfan database is a software that contains routines for the analysis of mutations identified in the
Gwenaëlle Collod-Béroud, Christophe B&...
95views more  BMCBI 2002»
11 years 11 months ago
The functional importance of disease-associated mutation
Background: For many years, scientists believed that point mutations in genes are the genetic switches for somatic and inherited diseases such as cystic fibrosis, phenylketonuria ...
Sean D. Mooney, Teri E. Klein
86views more  MOR 2006»
11 years 11 months ago
Evolutionary Stability for Large Populations and Backward Induction
It has been shown (Hart [2002]) that the backward induction (or subgame-perfect) equilibrium of a perfect information game is the unique stable outcome for dynamic models consisti...
Ziv Gorodeisky
142views more  BMCBI 2006»
11 years 11 months ago
RDMAS: a web server for RNA deleterious mutation analysis
Background: The diverse functions of ncRNAs critically depend on their structures. Mutations in ncRNAs disrupting the structures of functional sites are expected to be deleterious...
Wenjie Shu, Xiaochen Bo, Rujia Liu, Dongsheng Zhao...
75views more  BMCBI 2008»
11 years 11 months ago
A three-state prediction of single point mutations on protein stability changes
Background: A basic question of protein structural studies is to which extent mutations affect the stability. This question may be addressed starting from sequence and/or from str...
Emidio Capriotti, Piero Fariselli, Ivan Rossi, Rit...
136views more  BMCBI 2008»
11 years 11 months ago
An efficient method for the prediction of deleterious multiple-point mutations in the secondary structure of RNAs using suboptim
Background: RNAmute is an interactive Java application which, given an RNA sequence, calculates the secondary structure of all single point mutations and organizes them into categ...
Alexander Churkin, Danny Barash