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NAR
2000
118views more  NAR 2000»
13 years 4 months ago
DIP: the Database of Interacting Proteins
The Database of Interacting Proteins (DIP; http:// dip.doe-mbi.ucla.edu) is a database that documents experimentally determined protein
Ioannis Xenarios, Danny W. Rice, Lukasz Salw&iacut...
NAR
2000
109views more  NAR 2000»
13 years 4 months ago
The ASTRAL compendium for protein structure and sequence analysis
The ASTRAL compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. The SPACI scores included...
Steven E. Brenner, Patrice Koehl, Michael Levitt
JCB
2000
146views more  JCB 2000»
13 years 4 months ago
Bayesian Segmentation of Protein Secondary Structure
We present a novel method for predicting the secondary structure of a protein from its amino acid sequence. Most existing methods predict each position in turn based on a local wi...
Scott C. Schmidler, Jun S. Liu, Douglas L. Brutlag
JCB
2000
107views more  JCB 2000»
13 years 4 months ago
A Discriminative Framework for Detecting Remote Protein Homologies
A new method for detecting remote protein homologies is introduced and shown to perform well in classifying protein domains by SCOP superfamily. The method is a variant of support...
Tommi Jaakkola, Mark Diekhans, David Haussler
JCB
2000
101views more  JCB 2000»
13 years 4 months ago
Evaluation Measures of Multiple Sequence Alignments
Multiple sequence alignments (MSAs) are frequently used in the study of families of protein sequences or DNA/RNA sequences. They are a fundamental tool for the understanding of th...
Gaston H. Gonnet, Chantal Korostensky, Steven A. B...
BMCBI
2002
99views more  BMCBI 2002»
13 years 4 months ago
FunSpec: a web-based cluster interpreter for yeast
Background: For effective exposition of biological information, especially with regard to analysis of large-scale data types, researchers need immediate access to multiple categor...
Mark D. Robinson, Jörg Grigull, Naveed Mohamm...
CANDC
2004
ACM
13 years 4 months ago
Identification of related gene/protein names based on an HMM of name variations
Gene and protein names follow few, if any, true naming conventions and are subject to great variation in different occurrences of the same name. This gives rise to two important p...
Lana Yeganova, Lawrence H. Smith, W. John Wilbur
CANDC
2004
ACM
13 years 4 months ago
The iProClass integrated database for protein functional analysis
Increasingly, scientists have begun to tackle gene functions and other complex regulatory processes by studying organisms at the global scales for various levels of biological org...
Cathy H. Wu, Hongzhan Huang, Anastasia N. Nikolska...
CANDC
2004
ACM
13 years 4 months ago
iProLINK: an integrated protein resource for literature mining
The exponential growth of large-scale molecular sequence data and of the PubMed scientific literature has prompted active research in biological literature mining and information ...
Zhang-Zhi Hu, Inderjeet Mani, Vincent Hermoso, Hon...
BMCBI
2004
150views more  BMCBI 2004»
13 years 4 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty